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Chemical Name: 4-hydroxy-N-[(5E
Smiles: CC1CN(CCN1)C1=C(F)C=C2C(=C1OC)N(C=C(C2=O)C(O)=O)C1CC1
Pharmacokinetic Comparison of 20(R)- and 20(S)-Ginsenoside Rh1 and 20(R)- and 20(S)-Ginsenoside Rg3 in Rat Plasma following Oral Administration of Radix Ginseng Rubra and Sheng-Mai-San Extracts
low intrinsic microsome clearance
Formula: C57H62F2N10O10S2
RapaLink-1 ide hemihydrate Chemical Name: 4-hydroxy-N-[(5ERapaLink 1, the third generation bivalent mTOR inhibitor, combines Rapamycin (HY 10219) with MLN0128 (HY 13328, a second generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink 1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer derived, activating mutants of mTOR. RapaLink 1 can cross the blood brain barrier. RapaLink 1 binding to FKBP12 results in targeted and durable inhibition of
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